Mircera is an erythropoiesis-stimulating agent (ESA) indicated for the treatment of anemia associated with chronic kidney disease (CKD) in:

• Adult patients on dialysis and adult patients not on dialysis

• Pediatric patients 5 to 17 years of age on hemodialysis who are converting from another ESA after their hemoglobin level was stabilized with an ESA Limitations of Use Mircera is not indicated and is not recommended for use:

• In the treatment of anemia due to cancer chemotherapy

• As a substitute for RBC transfusions in patients who require immediate correction of anemia Mircera has not been shown to improve quality of life, fatigue, or patient well-being.

M-PK-00001196